Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 1/20 | 0.54 |
| ▸ | MME | P08473 | 2/20 | 0.49 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.49 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 2/20 | 0.41 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9486724 | 1.00 | CTRB1 (0.54) | CTRB1MMEMMEL1ECE1ALDH1A1 | |
| SCHEMBL9458948 | 0.89 | CTRB1 (0.58) | CTRB1MMEECE1ALDH1A1HPGD | |
| SCHEMBL9458824 | 0.86 | CTRB1 (0.49) | CTRB1MMEECE1ALDH1A1HPGD | |
| SCHEMBL9459001 | 0.83 | CTRB1 (0.44) | CTRB1ECE1ALDH1A1NPC1RAB9A | |
| SCHEMBL9459389 | 0.81 | HTT (0.57) | CTRB1MMEECE1ALDH1A1HPGD | |
| SCHEMBL9459228 | 0.80 | CTRB1 (0.53) | CTRB1ECE1ALDH1A1HPGDGAA | |
| SCHEMBL9459027 | 0.73 | SLC7A5 (0.42) | MMEMMEL1ALDH1A1HPGDTAS1R3 | |
| SCHEMBL9322253 | 0.72 | CTRB1 (0.53) | CTRB1MMEECE1 | |
| SCHEMBL11493557 | 0.71 | CTRB1 (1.00) | CTRB1MMEECE1 | |
| SCHEMBL9727410 | 0.70 | LMNA (0.45) | CTRB1MMEECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5232920-A | For treating hypertension and congestive heart failure in mammals | SCHERING CORPORATION (US) | 1993-08-03 | — | — | US | claimed |
| JP-56033646-A | — | — | None | — | — | JP | disclosed |
| EP-0563153-B1 | N-(MERCAPTOALKYL)AMIDES | SCHERING CORP (US) | 1995-03-15 | — | — | EP | disclosed |
| EP-0563153-A1 | N-(MERCAPTOALKYL)AMIDES. | SCHERING CORP (US) | 1993-10-06 | — | — | EP | disclosed |
| US-5232920-A | For treating hypertension and congestive heart failure in mammals | SCHERING CORPORATION (US) | 1993-08-03 | — | — | US | disclosed |
| US-5206119-A | Using nitrogen containing heterocyclic mercapto containing compound as stabilizer | KONICA CORPORATION (JP) | 1993-04-27 | — | — | US | disclosed |
| WO-1992011235-A1 | N-(MERCAPTOALKYL)AMIDES | SCHERING CORPORATION (US) | 1992-07-09 | — | — | WO | disclosed |
| JP-S5633646-A | PROCESSING METHOD FOR COLOR PHOTOGRAPHIC MATERIAL | FUJI PHOTO FILM CO LTD | 1981-04-04 | — | — | JP | disclosed |