Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.44 |
| ▸ | PPARA | Q07869 | 4/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | MME | P08473 | 3/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727406 | 1.00 | LMNA (0.45) | LMNACTRB1PPARAPPARGMME | |
| SCHEMBL9322253 | 0.79 | CTRB1 (0.53) | CTRB1PPARAPPARGMMEECE1 | |
| SCHEMBL9727233 | 0.78 | LMNA (0.43) | LMNAPPARAPPARGMME | |
| SCHEMBL9727232 | 0.78 | LMNA (0.43) | LMNAPPARAPPARGMME | |
| SCHEMBL9459389 | 0.73 | HTT (0.57) | CTRB1MMEECE1 | |
| SCHEMBL9458948 | 0.73 | CTRB1 (0.58) | LMNACTRB1PPARGMMEECE1 | |
| SCHEMBL10954718 | 0.72 | HTT (0.49) | PPARA | |
| SCHEMBL9486724 | 0.70 | CTRB1 (0.54) | CTRB1MMEECE1 | |
| SCHEMBL7357606 | 0.70 | CTRB1 (0.54) | CTRB1MMEECE1 | |
| SCHEMBL9459228 | 0.69 | CTRB1 (0.53) | CTRB1ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173506-A | For treating hypertension, congestive heart failure, edema or urogenital disorders in mammals | SCHERING CORPORATION (US) | 1992-12-22 | — | — | US | disclosed |