Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.41 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7357606 | 0.89 | CTRB1 (0.54) | CTRB1ALDH1A1HPGDECE1MME | |
| SCHEMBL9486724 | 0.89 | CTRB1 (0.54) | CTRB1ALDH1A1HPGDECE1MME | |
| SCHEMBL9458824 | 0.87 | CTRB1 (0.49) | CTRB1ALDH1A1HPGDECE1PPARG | |
| SCHEMBL9459228 | 0.86 | CTRB1 (0.53) | CTRB1ALDH1A1HPGDECE1MEN1 | |
| SCHEMBL9459389 | 0.84 | HTT (0.57) | CTRB1ALDH1A1HPGDECE1MME | |
| SCHEMBL9322253 | 0.75 | CTRB1 (0.53) | CTRB1ECE1PPARGMMEKDM4E | |
| SCHEMBL11493557 | 0.74 | CTRB1 (1.00) | CTRB1ECE1MMEROCK2RPS6KA5 | |
| SCHEMBL9727410 | 0.73 | LMNA (0.45) | CTRB1ECE1PPARGMMELMNA | |
| SCHEMBL9727406 | 0.73 | LMNA (0.45) | CTRB1ECE1PPARGMMELMNA | |
| SCHEMBL9458917 | 0.71 | HTT (0.42) | ALDH1A1HPGDPPARGMMEHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5232920-A | For treating hypertension and congestive heart failure in mammals | SCHERING CORPORATION (US) | 1993-08-03 | — | — | US | claimed |
| US-5232920-A | For treating hypertension and congestive heart failure in mammals | SCHERING CORPORATION (US) | 1993-08-03 | — | — | US | disclosed |