Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 3/20 | 0.53 |
| ▸ | MME | P08473 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | ECE1 | P42892 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727406 | 0.79 | LMNA (0.45) | CTRB1MMEPPARGPPARAECE1 | |
| SCHEMBL9727410 | 0.79 | LMNA (0.45) | CTRB1MMEPPARGPPARAECE1 | |
| SCHEMBL9458948 | 0.75 | CTRB1 (0.58) | CTRB1MMEPPARGECE1KDM4E | |
| SCHEMBL9459389 | 0.75 | HTT (0.57) | CTRB1MMEECE1 | |
| SCHEMBL9486724 | 0.72 | CTRB1 (0.54) | CTRB1MMEECE1 | |
| SCHEMBL7357606 | 0.72 | CTRB1 (0.54) | CTRB1MMEECE1 | |
| SCHEMBL9459228 | 0.72 | CTRB1 (0.53) | CTRB1ECE1 | |
| SCHEMBL9727172 | 0.72 | NLRP3 (0.48) | PPARANLRP3 | |
| SCHEMBL9458824 | 0.71 | CTRB1 (0.49) | CTRB1MMEPPARGECE1 | |
| SCHEMBL3130960 | 0.70 | KDM4E (0.43) | PPARGPPARAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543892-B1 | N-(MERCAPTOALKYL)UREAS AND CARBAMATES | SCHERING CORP (US) | 1994-11-23 | — | — | EP | disclosed |
| US-5356925-A | For cardiovascular and urogenital disorders | SCHERING CORPORATION (US) | 1994-10-18 | — | — | US | disclosed |
| US-5173506-A | For treating hypertension, congestive heart failure, edema or urogenital disorders in mammals | SCHERING CORPORATION (US) | 1992-12-22 | — | — | US | disclosed |
| WO-1992003410-A1 | N-(MERCAPTOALKYL)UREAS AND CARBAMATES | SCHERING CORPORATION (US) | 1992-03-05 | — | — | WO | disclosed |