Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 3/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.46 |
| ▸ | FCER2 | P06734 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7358298 | 0.89 | ALDH1A1 (0.61) | ALDH1A1KDM4EL3MBTL1TDP1MMP1 | |
| SCHEMBL7387251 | 0.86 | L3MBTL1 (0.64) | ALDH1A1KDM4EL3MBTL1TDP1MMP1 | |
| SCHEMBL7387248 | 0.86 | L3MBTL1 (0.64) | ALDH1A1KDM4EL3MBTL1TDP1MMP1 | |
| SCHEMBL7358304 | 0.83 | MMP3 (0.55) | ALDH1A1MMP1PSMB5FCER2 | |
| SCHEMBL13865261 | 0.82 | ALDH1A1 (0.62) | ALDH1A1KDM4EL3MBTL1TDP1MMP1 | |
| SCHEMBL7361179 | 0.81 | MME (0.53) | TDP1 | |
| SCHEMBL7355198 | 0.80 | MEN1 (0.55) | CYP3A4CYP2D6CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL7356367 | 0.80 | FPR2 (0.55) | ALDH1A1MMP1SMN1; SMN2HPGD | |
| SCHEMBL7358942 | 0.78 | KMT2A (0.53) | L3MBTL1PSMB5 | |
| SCHEMBL7361514 | 0.77 | BACE1 (0.48) | ALDH1A1L3MBTL1MMP1PSMB5FCER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753003-B1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5668128-A | INHIBITORS OF THIOL PROTEASE, PROPHYLAXIS AND TREATMENT OF BONE DISEASES, OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-09-16 | — | — | US | disclosed |
| EP-0753003-A1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995028416-A1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-26 | — | — | WO | disclosed |