Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MMP1 | P03956 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HLA-DRB1 | P01911 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7387251 | 1.00 | L3MBTL1 (0.64) | L3MBTL1ALDH1A1MMP1KDM4ETP53 | |
| SCHEMBL7362252 | 0.87 | MMP3 (0.50) | L3MBTL1MMP1PSMB5 | |
| SCHEMBL7358288 | 0.86 | ALDH1A1 (0.63) | L3MBTL1ALDH1A1MMP1KDM4ETDP1 | |
| SCHEMBL7358298 | 0.84 | ALDH1A1 (0.61) | L3MBTL1ALDH1A1MMP1KDM4ETDP1 | |
| SCHEMBL7361795 | 0.83 | L3MBTL1 (0.51) | L3MBTL1ALDH1A1KDM4EPSMB5 | |
| SCHEMBL7354780 | 0.83 | LMNA (0.49) | L3MBTL1ALDH1A1TDP1RAB9A | |
| SCHEMBL7359406 | 0.83 | MMP1 (0.49) | L3MBTL1MMP1EPHX2 | |
| SCHEMBL7356396 | 0.83 | CAPN1 (0.53) | ALDH1A1MMP1TP53MAPT | |
| SCHEMBL7354191 | 0.82 | FPR2 (0.54) | L3MBTL1ALDH1A1MMP1 | |
| SCHEMBL7361887 | 0.81 | MMP9 (0.55) | L3MBTL1ALDH1A1MAPTPSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753003-B1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5668128-A | INHIBITORS OF THIOL PROTEASE, PROPHYLAXIS AND TREATMENT OF BONE DISEASES, OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-09-16 | — | — | US | disclosed |
| EP-0753003-A1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995028416-A1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-26 | — | — | WO | disclosed |