Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MTTP | P55157 | 2/20 | 0.39 |
| ▸ | PRPS1 | P60891 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7356883 | 0.88 | NR1H4 (0.47) | NR1H4POLBMTTPKMT2AYTHDC1 | |
| SCHEMBL27249689 | 0.78 | ALDH1A1 (0.49) | NR1H4LCKMEN1KMT2ASYK | |
| SCHEMBL7355990 | 0.76 | EGLN3 (0.40) | NR1H4PRPS1SMN1; SMN2KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7357414 | 0.75 | PRPS1 (0.38) | NR1H4MTTPPRPS1ADORA2BSMN1; SMN2 | |
| SCHEMBL7353986 | 0.75 | KDM4E (0.36) | NR1H4PRPS1ADORA2BSMN1; SMN2KDM4E | |
| SCHEMBL7358428 | 0.75 | EGLN1 (0.40) | NR1H4MTTPPRPS1SMN1; SMN2KDM4E | |
| SCHEMBL7355082 | 0.75 | EGLN1 (0.45) | POLBMTTPSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7360967 | 0.74 | TSHR (0.46) | MTTPSMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL7360918 | 0.73 | CNR1 (0.43) | POLBSMN1; SMN2MEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL7362546 | 0.73 | TLR8 (0.41) | PRPS1ADORA2BSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003298-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS DOPAMINE RECEPTOR ANTAGONIST, 5-HT RECEPTOR AGONIST OR α1 RECEPTOR ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-02 | — | — | WO | disclosed |