Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | AQP4 | P55087 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MTTP | P55157 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354930 | 0.84 | NPC1 (0.52) | ALDH1A1HSD17B10HPGDMAPK1L3MBTL1 | |
| SCHEMBL7358547 | 0.81 | TSHR (0.39) | TSHRALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL7358428 | 0.81 | EGLN1 (0.40) | ALDH1A1KDM4ESMN1; SMN2NPSR1TP53 | |
| SCHEMBL7355082 | 0.81 | EGLN1 (0.45) | ALDH1A1HSD17B10HPGDMAPTKDM4E | |
| SCHEMBL7356668 | 0.77 | ALDH1A1 (0.48) | ALDH1A1HSD17B10HPGDL3MBTL1MAPT | |
| SCHEMBL7356630 | 0.76 | CHRNB2 (0.46) | NPC1RAB9AMTTPLMNA | |
| SCHEMBL7357340 | 0.76 | SMN1; SMN2 (0.45) | TSHRALDH1A1HSD17B10MAPTKDM4E | |
| SCHEMBL7355990 | 0.76 | EGLN3 (0.40) | TSHRALDH1A1MAPTKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7357414 | 0.75 | PRPS1 (0.38) | TSHRALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL7358971 | 0.74 | NR1H4 (0.46) | ALDH1A1MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003298-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS DOPAMINE RECEPTOR ANTAGONIST, 5-HT RECEPTOR AGONIST OR α1 RECEPTOR ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-02 | — | — | WO | disclosed |