Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAT2 | Q10469 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | AGER | Q15109 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7350242 | 0.90 | SMN1; SMN2 (0.43) | MGAT2ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL7352264 | 0.90 | KDM4E (0.52) | CHEK1NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL7355259 | 0.84 | AGER (0.53) | RAB9AALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL7348962 | 0.84 | ALDH1A1 (0.45) | NPC1RAB9AALDH1A1KDM4ECYP1A2 | |
| SCHEMBL8971536 | 0.83 | MGAT2 (0.44) | MGAT2SCN9ACHEK1ALDH1A1KDM4E | |
| SCHEMBL7354465 | 0.82 | SMN1; SMN2 (0.42) | ALDH1A1KDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7358509 | 0.81 | AGER (0.57) | RAB9AALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL7350522 | 0.76 | NPC1 (0.53) | NPC1RAB9AKDM4ELMNAMEN1 | |
| SCHEMBL7360982 | 0.74 | PGK1 (0.39) | NPC1RAB9AALDH1A1KDM4EMAPT | |
| SCHEMBL8970849 | 0.72 | KDM4E (0.50) | CHEK1ALDH1A1KDM4ECYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700383-B1 | NOVEL 1-PHENYLALKANONE 5-HT 4? RECEPTOR LIGANDS | SYNTEX INC (US) | 1998-09-23 | — | — | EP | disclosed |
| US-5763458-A | NERVOUS SYSTEM DISORDERS, ANXIETY, ANTIDEPRESSANTS AND COGNITION ACTIVATORS | SYNTEX (U.S.A.) INC. (US) | 1998-06-09 | — | — | US | disclosed |
| WO-1994027965-A1 | NOVEL 1-PHENYLALKANONE 5-HT4 RECEPTOR LIGANDS | SYNTEX (U.S.A.) INC. (US) | 1994-12-08 | — | — | WO | disclosed |