Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | BRD4 | O60885 | 3/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970918 | 0.91 | MTNR1B (0.43) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8971536 | 0.90 | MGAT2 (0.44) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8971982 | 0.89 | SMN1; SMN2 (0.41) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8971117 | 0.85 | AGER (0.47) | KDM4EALDH1A1LMNAPOLBCYP3A4 | |
| SCHEMBL7352264 | 0.82 | KDM4E (0.52) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8971265 | 0.82 | SMN1; SMN2 (0.42) | ALDH1A1LMNAMAPTKMT2AGAA | |
| SCHEMBL8970733 | 0.79 | AGER (0.43) | KDM4EALDH1A1LMNAPOLBCYP3A4 | |
| SCHEMBL8971050 | 0.75 | PGK1 (0.39) | KDM4EALDH1A1LMNAPOLBMAPT | |
| SCHEMBL7348962 | 0.74 | ALDH1A1 (0.45) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7359351 | 0.72 | MGAT2 (0.47) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700383-A1 | NOVEL 1-PHENYLALKANONE 5-HT 4? RECEPTOR LIGANDS | SYNTEX (U.S.A.) INC. (US) | 1996-03-13 | — | — | EP | disclosed |