Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8790973 | 0.88 | HRH3 (0.33) | SMN1; SMN2HRH3 | |
| SCHEMBL7359364 | 0.81 | BRD4 (0.46) | BRD4SMN1; SMN2LTA4HOPRD1HRH3 | |
| SCHEMBL8790348 | 0.80 | ACE2 (0.39) | SMN1; SMN2HRH3 | |
| SCHEMBL11079358 | 0.71 | TSHR (0.37) | HRH3 | |
| SCHEMBL7363075 | 0.68 | HRH3 (0.34) | BRD4HRH3 | |
| SCHEMBL7356483 | 0.68 | ALDH1A1 (0.36) | BRD4SMN1; SMN2HRH3 | |
| SCHEMBL2864044 | 0.67 | BRD4 (0.50) | BRD4SMN1; SMN2LTA4H | |
| SCHEMBL10232806 | 0.67 | BRD4 (0.42) | BRD4LTA4HHRH3 | |
| SCHEMBL7350613 | 0.66 | — | — | |
| SCHEMBL10280096 | 0.66 | BRD4 (0.53) | BRD4SMN1; SMN2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800516-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED (b)-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | NIPPON STEEL CORPORATION (JP) | 1997-10-15 | — | — | EP | disclosed |