Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | MMP12 | P39900 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3727147 | 0.89 | MMP8 (0.58) | MMP8MMP12MMP13TSHRHTT | |
| SCHEMBL7815324 | 0.80 | RORC (0.51) | MMP8MMP12MMP13TSHRHTT | |
| SCHEMBL3720690 | 0.79 | LMNA (0.57) | MMP8MMP12MMP13HTTHSD11B1 | |
| SCHEMBL23498098 | 0.79 | TSHR (0.63) | TSHRALDH1A1KDM4EPOLBLMNA | |
| SCHEMBL29784717 | 0.79 | TSHR (0.63) | TSHRALDH1A1KDM4EPOLBLMNA | |
| SCHEMBL7505424 | 0.79 | MMP8 (0.56) | MMP8MMP12MMP13TSHRHTT | |
| SCHEMBL4612455 | 0.79 | MMP8 (0.56) | MMP8MMP12MMP13TSHRHTT | |
| SCHEMBL6939720 | 0.79 | MMP8 (0.53) | MMP8MMP12MMP13TSHRHTT | |
| SCHEMBL6944021 | 0.79 | MMP8 (0.53) | MMP8MMP12MMP13TSHRHTT | |
| SCHEMBL2705837 | 0.78 | HCRTR1 (0.64) | TSHRHTTKDM4ECASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1033983-A1 | CYCLIC AMINO ACID DERIVATIVES AS CELL ADHESION INHIBITORS | Merck & Co., Inc. (US) | 2000-09-13 | — | — | EP | disclosed |
| WO-1999026615-A1 | CYCLIC AMINO ACID DERIVATIVES AS CELL ADHESION INHIBITORS | MERCK & CO., INC. (US) | 1999-06-03 | — | — | WO | disclosed |