SCHEMBL736043

SCHEMBL736043

CC1CC2CCC(C1)N2C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.57
LMNA P02545 1/20 0.57
SLC6A2 P23975 6/20 0.39
SLC6A3 Q01959 6/20 0.39
CHRM1 P11229 7/20 0.36
CHRM3 P20309 4/20 0.36
SLC6A4 P31645 4/20 0.36
DRD3 P35462 4/20 0.36
CHRM2 P08172 3/20 0.36
HRH1 P35367 2/20 0.36
ADRA2A P08913 2/20 0.36
DRD2 P14416 2/20 0.36
ADRA2B P18089 2/20 0.36
ADRA2C P18825 2/20 0.36
HRH2 P25021 2/20 0.36
ADRA1D P25100 2/20 0.36
HTR2A P28223 2/20 0.36
HTR6 P50406 2/20 0.36
SIGMAR1 Q99720 2/20 0.36
CHRM4 P08173 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14424486 1.00 CYP2C9 (0.57) CYP2C9LMNASLC6A2SLC6A3CHRM1
SCHEMBL12463068 1.00 CYP2C9 (0.57) CYP2C9LMNASLC6A2SLC6A3CHRM1
SCHEMBL22631620 1.00 CYP2C9 (0.57) CYP2C9LMNASLC6A2SLC6A3CHRM1
SCHEMBL17399388 1.00 CYP2C9 (0.57) CYP2C9LMNASLC6A2SLC6A3CHRM1
SCHEMBL23100945 1.00 CYP2C9 (0.57) CYP2C9LMNASLC6A2SLC6A3CHRM1
SCHEMBL756764 1.00 CYP2C9 (0.57) CYP2C9LMNASLC6A2SLC6A3CHRM1
SCHEMBL23101821 1.00 CYP2C9 (0.57) CYP2C9LMNASLC6A2SLC6A3CHRM1
SCHEMBL13243111 0.88 LMNA (0.46) CYP2C9LMNASLC6A2SLC6A3CHRM1
SCHEMBL16727365 0.88 MAPK1 (0.46) CYP2C9LMNASLC6A2SLC6A3CHRM1
SCHEMBL14310687 0.88 MAPK1 (0.46) CYP2C9LMNASLC6A2SLC6A3CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 349 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7662849-B2 Amidino compounds as cysteine protease inhibitors VIROBAY, INC. (US) 2010-02-16 US claimed
US-20060264464-A1 Amidino compounds as cysteine protease inhibitors QUEST DIAGNOSTICS INVESTMENTS LLC 2006-11-23 US claimed
US-4432983-A GASTRIC ACID INHIBITORS RESEARCH CORPORATION (US) 1984-02-21 US claimed
US-20240228478-A1 COMPOUNDS AND METHODS OF USE TANGO THERAPEUTICS, INC. 2024-07-11 US disclosed
EP-4397661-A1 COMPOUND FOR DEGRADATION OF BCL-2 FAMILY PROTEINS AND MEDICAL APPLICATION THEREOF Xizang Haisco Pharmaceutical Co., Ltd. (CN) 2024-07-10 EP disclosed
EP-3967695-B1 1-(7-(QUINAZOLIN-4-YL)-2,7-DIAZASPIRO[3.5]NONAN-2-YL)PROP-2-EN-1-ONE DERIVATIVES AS KRAS INHIBITORS FOR THE TREATMENT OF CANCER BETTA PHARMACEUTICALS CO LTD (CN) 2024-01-17 EP disclosed
US-11873298-B2 Compounds and uses thereof JANSSEN PHARMACEUTICA NV (BE) 2024-01-16 US disclosed
WO-2024009232-A1 SUBSTITUTED N-(PYRIDIN-2-YL)ACETAMIDE DERIVATIVES AS CDK12/13 INHIBITORS AURIGENE ONCOLOGY LIMITED (IN) 2024-01-11 WO disclosed
WO-2024003535-A2 COMPOUNDS UNIVERSITY OF DUNDEE (GB) 2024-01-04 WO disclosed
US-20230357193-A1 COMPOUND CAPABLE OF INHIBITING AND DEGRADING ANDROGEN RECEPTORS, AND PHARMACEUTICAL COMPOSITIONS AND PHARMACEUTICAL USES THEREOF XIZANG HAISCO PHARMACEUTICALS CO., LTD. (CN) 2023-11-09 US disclosed
US-20230357259-A1 BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) 2023-11-09 US disclosed
US-20040127426-A1 Peptidic compounds as cysteine protease inhibitors AXYS PHARMACEUTICALS, INC. 2004-07-01 US disclosed
EP-1429811-A1 THEURAPEUTIC TROPANE COMPOUNDS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2004-06-23 EP disclosed
WO-2004000838-A1 PEPTIDIC COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS AXYS PHARMACEUTICALS, INC. (US) 2003-12-31 WO disclosed
WO-2003099783-A2 TROPANE COMPOUNDS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2003-12-04 WO disclosed
WO-2003015830-A1 THEURAPEUTIC TROPANE COMPOUNDS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2003-02-27 WO disclosed
EP-0996619-A1 TROPANE ANALOGS AND METHODS FOR INHIBITION OF MONOAMINE TRANSPORT ORGANIX, INC. (US) 2000-05-03 EP disclosed
WO-1999002526-A1 TROPANE ANALOGS AND METHODS FOR INHIBITION OF MONOAMINE TRANSPORT ORGANIX, INC. (US) 1999-01-21 WO disclosed
US-5770180-A COCAINE ORGANIX, INC. (US) 1998-06-23 US disclosed
EP-0309424-A2 New amidino derivatives ISTITUTO DE ANGELI S.p.A. (IT) 1989-03-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357259-A1 BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF DOCK11, PAICS, RHOA CYP2C9 4293/4885LMNA 1356/4885SLC6A2 3747/4885
US-20230357193-A1 COMPOUND CAPABLE OF INHIBITING AND DEGRADING ANDROGEN RECEPTORS, AND PHARMACEUTICAL COMPOSITIONS AND PHARMACEUTICAL USES THEREOF AR, CYP17A1, KLK3 CYP2C9 87/4885LMNA 1905/4885SLC6A2 2931/4885
US-11873298-B2 Compounds and uses thereof NLN, ACHE, CLN6 CYP2C9 1658/4885LMNA 1966/4885SLC6A2 100/4885
US-20060264464-A1 Amidino compounds as cysteine protease inhibitors CTSF, CTSB, CTSS CYP2C9 1835/4885LMNA 1267/4885SLC6A2 4477/4885
US-20240228478-A1 COMPOUNDS AND METHODS OF USE F12, C1R, ABCG2 CYP2C9 10/4885LMNA 1976/4885SLC6A2 885/4885
US-20040127426-A1 Peptidic compounds as cysteine protease inhibitors CTSF, CTSB, CTSS CYP2C9 3015/4885LMNA 1983/4885SLC6A2 4572/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.