Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 5/20 | 0.32 |
| ▸ | MMP1 | P03956 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7365072 | 0.71 | MMP3 (0.34) | MMP3MMP1ALDH1A1MAPTHPGD | |
| SCHEMBL7399055 | 0.70 | MMP3 (0.44) | MMP3MMP1 | |
| SCHEMBL8902722 | 0.69 | MMP3 (0.46) | MMP3MMP1 | |
| SCHEMBL7562073 | 0.69 | MMP3 (0.44) | MMP3MMP1 | |
| SCHEMBL7481678 | 0.68 | MMP3 (0.42) | MMP3MMP1 | |
| SCHEMBL7275440 | 0.66 | SLC15A1 (0.47) | ALDH1A1HSD17B10 | |
| SCHEMBL7420644 | 0.65 | ANPEP (0.43) | ALDH1A1HSD17B10 | |
| SCHEMBL7426285 | 0.65 | MMP3 (0.44) | MMP3MMP1ALDH1A1MAPTHPGD | |
| SCHEMBL8705956 | 0.64 | MMP3 (0.48) | MMP3MMP1ALDH1A1MAPTHPGD | |
| SCHEMBL30254757 | 0.63 | SLC15A1 (0.40) | ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998025949-A1 | SUBSTITUTED 5-AMINO-1,3,4-THIADIAZOLE-2-THIONES | PROSCRIPT, INC. (US) | 1998-06-18 | — | — | WO | disclosed |
| EP-0845002-A2 | AMINO ACID AMIDES OF 5-AMINO-1,3,4-THIADIAZONES AND THEIR USE AS INHIBITORS FOR MATRIX METALLOPROTEINASES | PROSCRIPT, INC. (US) | 1998-06-03 | — | — | EP | disclosed |
| WO-1996040745-A2 | AMINO ACID AMIDES OF 5-AMINO-1,3,4-THIADIAZONES AND THEIR USE AS INHIBITORS FOR MATRIX METALLOPROTEINASES | PROSCRIPT, INC. (US) | 1996-12-19 | — | — | WO | disclosed |