Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.37 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360351 | 0.87 | PARP14 (0.40) | FAAHEPHX2MAPTPOLBNPSR1 | |
| SCHEMBL7365927 | 0.82 | GRIN2D (0.46) | EPHX2MAPTGRIN2DGRIN3BGRIN1 | |
| SCHEMBL4096230 | 0.74 | TPSAB1 (0.43) | TSHRALDH1A1KMT2AMEN1GRIN2B | |
| SCHEMBL7361819 | 0.73 | VNN1 (0.38) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7363740 | 0.73 | GRIN2D (0.44) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL3145712 | 0.71 | SIGMAR1 (0.44) | EPHX2KMT2AMEN1 | |
| SCHEMBL6164881 | 0.70 | LTA4H (0.49) | KMT2AMEN1 | |
| SCHEMBL3279457 | 0.70 | ALDH1A1 (0.41) | FAAHMAPTPOLBNPC1RAB9A | |
| SCHEMBL3137377 | 0.70 | TPSAB1 (0.43) | TSHRALDH1A1GRIN2B | |
| SCHEMBL7364168 | 0.68 | PRSS1 (0.40) | EPHX2PARP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046553-A1 | THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | disclosed |