Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7366561 | 0.79 | HTT (0.42) | ALDH1A1NPSR1MEN1KMT2AMMP1 | |
| SCHEMBL6379273 | 0.78 | NPC1 (0.38) | NPC1MTNR1AMTNR1BALDH1A1F2 | |
| SCHEMBL6380461 | 0.70 | MTNR1A (0.50) | NPC1MTNR1AMTNR1BALDH1A1CA1 | |
| SCHEMBL7361327 | 0.70 | MMP1 (0.43) | CA1CA2CA9MMP1MMP2 | |
| SCHEMBL12264723 | 0.69 | MMP2 (0.49) | NPC1MTNR1AMTNR1BALDH1A1CA1 | |
| SCHEMBL7075160 | 0.67 | MTNR1A (0.47) | NPC1MTNR1AMTNR1BALDH1A1CA1 | |
| SCHEMBL7074737 | 0.65 | TAS1R3 (0.44) | NPC1MTNR1AMTNR1BALDH1A1CA1 | |
| Cadaverine Tartrate SCHEMBL29661248 | 0.65 | MTNR1A (0.51) | NPC1MTNR1AMTNR1BALDH1A1CA1 | |
| SCHEMBL7073559 | 0.64 | PDE4B (0.48) | NPC1MTNR1AMTNR1BALDH1A1LDHA | |
| SCHEMBL772862 | 0.64 | CA1 (0.53) | NPC1MTNR1AMTNR1BALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929519-A1 | $g(b)-SULFONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS | PHARMACIA & UPJOHN COMPANY (US) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998013340-A1 | β-SULFONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS | PHARMACIA & UPJOHN COMPANY (US) | 1998-04-02 | — | — | WO | disclosed |