Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 5/20 | 0.44 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361776 | 0.84 | MAPT (0.50) | PKMMAPK1RAB9AKDM4EHCAR3 | |
| SCHEMBL7355699 | 0.82 | KAT2B (0.58) | PKMMAPK1RAB9AHCAR3ALDH1A1 | |
| SCHEMBL7351297 | 0.82 | ALDH1A1 (0.57) | PKMRAB9AALDH1A1NPC1MAPT | |
| SCHEMBL7349273 | 0.82 | KCNMA1 (0.50) | PKMMAPK1RAB9AHCAR3SERPINE1 | |
| SCHEMBL7354885 | 0.79 | KMT2A (0.58) | PKMMAPK1RAB9ASERPINE1ALDH1A1 | |
| SCHEMBL420259 | 0.79 | ALDH1A1 (0.62) | PKMMAPK1RAB9AKDM4EHCAR3 | |
| SCHEMBL29670495 | 0.79 | ALDH1A1 (0.62) | PKMMAPK1RAB9AKDM4EHCAR3 | |
| SCHEMBL26324521 | 0.79 | HCAR3 (0.63) | PKMMAPK1RAB9AKDM4EHCAR3 | |
| SCHEMBL594213 | 0.78 | HCAR3 (0.61) | PKMMAPK1RAB9AKDM4EHCAR3 | |
| SCHEMBL16423449 | 0.78 | ALDH1A1 (0.60) | PKMMAPK1RAB9AKDM4EABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288065-B1 | CENTRAL NERVOUS SYSTEM DISORDERS; PARKINSON*S AND ALZHEIMER*S DISEASE | SCHERING AKTIENGESEELLSCHAFT (DE) | 2001-09-11 | — | — | US | disclosed |
| US-6057304-A | Quinoxaline-phosphonic acid derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |
| CN-1038840-C | para-dinitrogen naphthalene derivative, its preparation method and its medical use | SCHERING AG (DE) | 1998-06-24 | — | — | CN | disclosed |
| EP-0565683-A1 | QUINOXALINE DERIVATES WITH AFFINITY FOR QUISQUALATE-RECEPTORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-10-20 | — | — | EP | disclosed |
| CN-1072929-A | Para-dinitronaphthalene derivative, preparation method and medical application thereof | SCHERING AG (DE) | 1993-06-09 | — | — | CN | disclosed |
| WO-1993008173-A1 | QUINOXALINE DERIVATES WITH AFFINITY FOR QUISQUALATE-RECEPTORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-04-29 | — | — | WO | disclosed |