Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 3/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.35 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.35 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361627 | 0.87 | CTSB (0.52) | CTSBCTSL | |
| SCHEMBL7270308 | 0.81 | ALDH1A1 (0.42) | CTRB1LTA4H | |
| SCHEMBL7279585 | 0.80 | CA2 (0.43) | CTRB1ANPEPRNPEPDNPEP | |
| SCHEMBL7362341 | 0.80 | MAPK1 (0.56) | CTRB1ANPEPRNPEPDNPEP | |
| SCHEMBL7364429 | 0.77 | REN (0.42) | CTRB1ANPEPRNPEPDNPEP | |
| SCHEMBL7358373 | 0.75 | CTSB (0.44) | CTSBCTRB1 | |
| SCHEMBL7358371 | 0.75 | CTSB (0.44) | CTSBCTRB1 | |
| SCHEMBL7421175 | 0.72 | LTA4H (0.54) | LTA4H | |
| SCHEMBL18568243 | 0.70 | ALPI (0.51) | LTA4HANPEPRNPEPDNPEP | |
| SCHEMBL5689533 | 0.70 | CTSB (0.63) | CTSBCTRB1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415981-A4 | RETROVIRAL PROTEASE INHIBITORS | — | 1991-10-09 | — | — | EP | disclosed |
| EP-0415981-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| WO-1989010752-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |