Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363740 | 0.84 | GRIN2D (0.44) | LMNA | |
| SCHEMBL7361819 | 0.84 | VNN1 (0.38) | LMNAMAPTDPP4DPP8DPP9 | |
| SCHEMBL7365153 | 0.75 | LMNA (0.36) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL5206416 | 0.74 | MAPT (0.51) | ALDH1A1LMNASMN1; SMN2MAPTMAPK1 | |
| SCHEMBL5206407 | 0.74 | MAPT (0.51) | ALDH1A1LMNASMN1; SMN2MAPTMAPK1 | |
| SCHEMBL28417404 | 0.69 | NPC1 (0.48) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL7365927 | 0.69 | GRIN2D (0.46) | LMNAMAPTTDP1 | |
| SCHEMBL4096230 | 0.68 | TPSAB1 (0.43) | ALDH1A1TDP1KMT2A | |
| SCHEMBL10636212 | 0.68 | SMN1; SMN2 (0.50) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL7361150 | 0.68 | FAAH (0.40) | ALDH1A1SMN1; SMN2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046553-A1 | THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | disclosed |