Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | MMP1 | P03956 | 3/20 | 0.44 |
| ▸ | FCER2 | P06734 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7387248 | 0.87 | L3MBTL1 (0.64) | L3MBTL1MMP1PSMB5 | |
| SCHEMBL7387251 | 0.87 | L3MBTL1 (0.64) | L3MBTL1MMP1PSMB5 | |
| SCHEMBL7358304 | 0.86 | MMP3 (0.55) | MMP3BCHEKMT2AATMMMP1 | |
| SCHEMBL7359278 | 0.85 | CYP1A2 (0.53) | L3MBTL1PSMB5 | |
| SCHEMBL7359406 | 0.85 | MMP1 (0.49) | L3MBTL1ATMMMP1FCER2KLKB1 | |
| SCHEMBL7358297 | 0.84 | MMP3 (0.53) | MMP3BCHEKMT2AATMMMP1 | |
| SCHEMBL7361188 | 0.83 | BACE1 (0.45) | L3MBTL1PSMB5 | |
| SCHEMBL7363926 | 0.83 | L3MBTL1 (0.47) | L3MBTL1KMT2APSMB5 | |
| SCHEMBL7354485 | 0.82 | CTSS (0.43) | L3MBTL1ATM | |
| SCHEMBL7361795 | 0.82 | L3MBTL1 (0.51) | L3MBTL1KMT2AATMMEN1PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753003-B1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5668128-A | INHIBITORS OF THIOL PROTEASE, PROPHYLAXIS AND TREATMENT OF BONE DISEASES, OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-09-16 | — | — | US | disclosed |
| EP-0753003-A1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995028416-A1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-26 | — | — | WO | disclosed |