Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | FPR2 | P25090 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354191 | 0.87 | FPR2 (0.54) | L3MBTL1FPR2ATMALDH1A1MEN1 | |
| SCHEMBL7360469 | 0.85 | L3MBTL1 (0.44) | L3MBTL1FPR2ALDH1A1HSD17B10GAA | |
| SCHEMBL8307163 | 0.84 | USP30 (0.42) | L3MBTL1FPR2USP30ALDH1A1MEN1 | |
| SCHEMBL7387248 | 0.83 | L3MBTL1 (0.64) | L3MBTL1ALDH1A1PSMB5KDM4E | |
| SCHEMBL7387251 | 0.83 | L3MBTL1 (0.64) | L3MBTL1ALDH1A1PSMB5KDM4E | |
| SCHEMBL7354780 | 0.82 | LMNA (0.49) | L3MBTL1FPR2ALDH1A1KMT2AGAA | |
| SCHEMBL7362252 | 0.82 | MMP3 (0.50) | L3MBTL1ATMMEN1KMT2APSMB5 | |
| SCHEMBL7359406 | 0.82 | MMP1 (0.49) | L3MBTL1ATM | |
| SCHEMBL7356396 | 0.82 | CAPN1 (0.53) | FPR2USP30ALDH1A1MEN1KMT2A | |
| SCHEMBL7362837 | 0.80 | FPR2 (0.52) | L3MBTL1FPR2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753003-B1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5668128-A | INHIBITORS OF THIOL PROTEASE, PROPHYLAXIS AND TREATMENT OF BONE DISEASES, OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-09-16 | — | — | US | disclosed |
| EP-0753003-A1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995028416-A1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-26 | — | — | WO | disclosed |