Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.42 |
| ▸ | LAP3 | P28838 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.38 |
| ▸ | HRAS | P01112 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7355861 | 0.80 | PSMB1 (0.41) | LTA4HLAP3LNPEPHRASPPARG | |
| SCHEMBL7426285 | 0.80 | MMP3 (0.44) | MMP3MMP1 | |
| SCHEMBL7358575 | 0.79 | PTPN1 (0.46) | LTA4HLNPEPHRASPPARGMMP3 | |
| SCHEMBL7362596 | 0.78 | LTA4H (0.40) | LTA4HLAP3MAOBLNPEPPPARG | |
| SCHEMBL7358546 | 0.78 | LTA4H (0.41) | LTA4HLAP3LNPEPPPARGPPARA | |
| SCHEMBL8902722 | 0.77 | MMP3 (0.46) | LTA4HLNPEPMMP3MMP1 | |
| SCHEMBL7366301 | 0.77 | MMP3 (0.47) | LTA4HLNPEPMMP3MMP1 | |
| SCHEMBL7388232 | 0.76 | MMP3 (0.47) | LTA4HLAP3LNPEPMMP3MMP1 | |
| SCHEMBL7359871 | 0.76 | MMP3 (0.44) | LTA4HMMP3MMP1 | |
| SCHEMBL7394273 | 0.75 | ITGB3 (0.44) | LNPEPHRASPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0845002-A2 | AMINO ACID AMIDES OF 5-AMINO-1,3,4-THIADIAZONES AND THEIR USE AS INHIBITORS FOR MATRIX METALLOPROTEINASES | PROSCRIPT, INC. (US) | 1998-06-03 | — | — | EP | disclosed |
| US-5677282-A | ENZYME INHIBITOR; OSTEOARTHRITIS AND RHEUMATIC DISORDERS | PROSCRIPT, INC. (US) | 1997-10-14 | — | — | US | disclosed |
| WO-1996040745-A2 | AMINO ACID AMIDES OF 5-AMINO-1,3,4-THIADIAZONES AND THEIR USE AS INHIBITORS FOR MATRIX METALLOPROTEINASES | PROSCRIPT, INC. (US) | 1996-12-19 | — | — | WO | disclosed |