Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.41 |
| ▸ | LAP3 | P28838 | 1/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.41 |
| ▸ | MMP3 | P08254 | 3/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.37 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.37 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.37 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7358535 | 0.94 | MMP3 (0.41) | MMP3PPARAMMP1 | |
| SCHEMBL7355861 | 0.84 | PSMB1 (0.41) | LTA4HLAP3LNPEPMMP3PTPN1 | |
| SCHEMBL7358575 | 0.83 | PTPN1 (0.46) | LTA4HLNPEPMMP3PTPN1PPARG | |
| SCHEMBL7362596 | 0.81 | LTA4H (0.40) | LTA4HLAP3LNPEPMMP3PPARG | |
| SCHEMBL7426285 | 0.81 | MMP3 (0.44) | MMP3MMP1 | |
| SCHEMBL7394273 | 0.79 | ITGB3 (0.44) | LNPEPPPARGERAP2 | |
| SCHEMBL7357685 | 0.79 | MMP3 (0.44) | MMP3MMP1 | |
| SCHEMBL7358708 | 0.79 | MMP3 (0.42) | MMP3MMP1 | |
| SCHEMBL7362591 | 0.78 | LTA4H (0.42) | LTA4HLAP3LNPEPMMP3PPARG | |
| SCHEMBL7361335 | 0.78 | MMP3 (0.42) | LNPEPMMP3MMP1ERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0845002-A2 | AMINO ACID AMIDES OF 5-AMINO-1,3,4-THIADIAZONES AND THEIR USE AS INHIBITORS FOR MATRIX METALLOPROTEINASES | PROSCRIPT, INC. (US) | 1998-06-03 | — | — | EP | disclosed |
| US-5677282-A | ENZYME INHIBITOR; OSTEOARTHRITIS AND RHEUMATIC DISORDERS | PROSCRIPT, INC. (US) | 1997-10-14 | — | — | US | disclosed |
| WO-1996040745-A2 | AMINO ACID AMIDES OF 5-AMINO-1,3,4-THIADIAZONES AND THEIR USE AS INHIBITORS FOR MATRIX METALLOPROTEINASES | PROSCRIPT, INC. (US) | 1996-12-19 | — | — | WO | disclosed |