Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.33 |
| ▸ | PPARA | Q07869 | 13/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363592 | 0.90 | FAAH (0.34) | FAAH | |
| SCHEMBL7430870 | 0.80 | PPARG (0.32) | PPARGPPARAFAAHCES1 | |
| SCHEMBL6806939 | 0.80 | CTSL (0.36) | PPARGPPARA | |
| SCHEMBL7363581 | 0.72 | PPARG (0.40) | PPARGPPARAFAAHCES1 | |
| SCHEMBL6801144 | 0.71 | CTSL (0.33) | PPARGFAAH | |
| SCHEMBL7250425 | 0.69 | MMP1 (0.34) | FAAHCES1 | |
| SCHEMBL6806942 | 0.68 | CTSL (0.43) | — | |
| SCHEMBL7661859 | 0.66 | PPARG (0.35) | PPARGPPARACES1 | |
| SCHEMBL6918534 | 0.63 | BMP1 (0.34) | FAAHCES1 | |
| SCHEMBL6918530 | 0.63 | BMP1 (0.34) | FAAHCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1159273-A1 | COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CATHEPSIN S | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000051998-A1 | COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CATHEPSIN S | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2000-09-08 | — | — | WO | disclosed |