Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | TMPRSS11D | O60235 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7934109 | 0.88 | ITGB3 (0.42) | GFERITGB3ITGA2BPOLB | |
| SCHEMBL7365564 | 0.88 | ITGB3 (0.42) | GFERITGB3ITGA2BPOLB | |
| SCHEMBL7365560 | 0.88 | ITGB3 (0.42) | GFERITGB3ITGA2BPOLB | |
| SCHEMBL7367244 | 0.86 | RORC (0.36) | GRM5CYP3A4CYP2D6CYP2C9TSHR | |
| SCHEMBL7370704 | 0.85 | CYP2D6 (0.38) | GAAMAPTITGB3ITGA2BGRM5 | |
| SCHEMBL7362643 | 0.83 | MC4R (0.37) | MAPTPOLBTSHRKMT2AALDH1A1 | |
| SCHEMBL7369431 | 0.83 | L3MBTL1 (0.34) | GFERGAAMAPTCYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL7362335 | 0.82 | MC4R (0.37) | MAPTPOLBTSHRKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL7371045 | 0.82 | ALDH1A1 (0.39) | GFERGAAMAPTMAPK1CYP3A4 | |
| SCHEMBL7362301 | 0.82 | SMN1; SMN2 (0.39) | GAAMAPTALOX15MAPK1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970071-A1 | 2-PEPERAZINONE-1-ACETIC ACID DERIVATIVES AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998039324-A1 | 2-PEPERAZINONE-1-ACETIC ACID DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-11 | — | — | WO | disclosed |