Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7365852 | 0.80 | ACHE (0.52) | ACHE | |
| SCHEMBL7365661 | 0.78 | DRD2 (0.43) | ACHE | |
| SCHEMBL7366544 | 0.72 | SIGMAR1 (0.61) | — | |
| SCHEMBL7367469 | 0.72 | GBA1 (0.41) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10667389 | 0.71 | PARP1 (0.49) | LTA4H | |
| SCHEMBL7438133 | 0.69 | ALOX5 (0.43) | ACHE | |
| SCHEMBL14454753 | 0.68 | HTR2C (0.46) | LTA4H | |
| SCHEMBL14454752 | 0.67 | HTR2C (0.46) | LTA4H | |
| SCHEMBL11188819 | 0.65 | MEN1 (0.34) | SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL10834103 | 0.64 | MEN1 (0.33) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997028157-A1 | NOVEL PIPERIDINE DERIVATIVES 4-SUBSTITUTED BY AN IMIDAZOLIDIN-2-ON-1-YL-ETHYL, TETRAHYDROPYRIMIDIN-2-ON-1-YL-ETHYL AND 1,3-DIAZEPIN-2-ON-1-YL-ETHYL GROUP, AND USE THEREOF AS α2-ADRENERGIC RECEPTOR ANTAGONISTS | PIERRE FABRE MEDICAMENT (FR) | 1997-08-07 | — | — | WO | disclosed |