Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | ACE | P12821 | 2/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.46 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369936 | 0.95 | PTPN1 (0.51) | PTPN1ACEAGTR2GPR132CA2 | |
| SCHEMBL7365722 | 0.86 | LNPEP (0.49) | PTPN1ACEAGTR2CA2CA1 | |
| SCHEMBL7370637 | 0.81 | AGTR2 (0.48) | AGTR2CA2CA1KMT2AMEN1 | |
| SCHEMBL7365573 | 0.79 | PTPN1 (0.59) | PTPN1ACEAGTR2GPR132CA2 | |
| SCHEMBL7365391 | 0.77 | AGTR2 (0.44) | AGTR2CA2CA1KMT2AMEN1 | |
| SCHEMBL7444103 | 0.77 | AGTR2 (0.44) | AGTR2CA2CA1KMT2AMEN1 | |
| SCHEMBL111235 | 0.72 | ACE (0.76) | PTPN1ACEGPR132CA2CA1 | |
| SCHEMBL111236 | 0.72 | ACE (0.76) | PTPN1ACEGPR132CA2CA1 | |
| SCHEMBL528464 | 0.72 | ACE (0.76) | PTPN1ACEGPR132CA2CA1 | |
| Hydrochloric Acid SCHEMBL10622640 | 0.71 | ACE (0.74) | PTPN1ACEGPR132CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920307-A2 | DERIVATES FROM BISARYLTETRACARBONACID, AND PHARMARCEUTICAL PRODUCT CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998006386-A2 | DERIVATES FROM BISARYLTETRACARBONACID, AND PHARMARCEUTICAL PRODUCT CONTAINING THEM | ROCHE DIAGNOSTICS GMBH (DE) | 1998-02-19 | — | — | WO | disclosed |