Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.70 |
| ▸ | TEK | Q02763 | 8/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PDE2A | O00408 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.46 |
| ▸ | GCGR | P47871 | 3/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | RAF1 | P04049 | 2/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369909 | 0.84 | NPC1 (0.52) | TGFBR1TEKNPC1RAB9APDE2A | |
| Sb-202474 SCHEMBL6469103 | 0.82 | TGFBR1 (1.00) | TGFBR1TEKMAPK14MAPK13MAPK12 | |
| Sb-202474 SCHEMBL31118901 | 0.81 | TGFBR1 (0.97) | TGFBR1TEKMAPK14MAPK13MAPK12 | |
| SCHEMBL7371189 | 0.79 | TGFBR1 (0.70) | TGFBR1NPC1MAPK14MAPK13MAPK12 | |
| SCHEMBL7369293 | 0.77 | CYP3A4 (0.52) | NPC1PDE2ANPY5R | |
| SCHEMBL4133106 | 0.74 | NPC1 (0.64) | NPC1RAB9A | |
| SCHEMBL941325 | 0.73 | NOX1 (0.61) | TEKPDE2AMAPK14MAPK13MAPK12 | |
| SCHEMBL29363231 | 0.73 | NOX1 (0.61) | TEKPDE2AMAPK14MAPK13MAPK12 | |
| SCHEMBL7368577 | 0.72 | NPC1 (0.47) | TGFBR1TEKNPC1RAB9AMAPK14 | |
| SCHEMBL7370913 | 0.71 | NPY5R (0.57) | NPC1RAB9APDE2ANPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |