Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.42 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.42 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 2/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7365934 | 0.81 | LIPE (0.44) | GAALIPEL3MBTL1CTSLHTT | |
| SCHEMBL694641 | 0.81 | LIPE (0.44) | GAALIPEL3MBTL1CTSLHTT | |
| SCHEMBL477283 | 0.80 | LIPE (0.42) | GAALIPEL3MBTL1CTSL | |
| SCHEMBL27497088 | 0.79 | FKBP5 (0.48) | KDM4EGAAPOLBCRBNFKBP5 | |
| SCHEMBL1576452 | 0.76 | CTSK (0.40) | GAALIPEL3MBTL1CTSLNFKB1 | |
| SCHEMBL5651167 | 0.75 | LIPE (0.39) | GAALIPEL3MBTL1CTSLNFKB1 | |
| SCHEMBL21233487 | 0.74 | HPGD (0.50) | KDM4EGAAPOLBCRBNDDB1 | |
| SCHEMBL7449417 | 0.74 | L3MBTL1 (0.37) | KDM4EGAAPOLBL3MBTL1CTSL | |
| SCHEMBL26266001 | 0.74 | LIPE (0.42) | GAALIPEL3MBTL1CTSLNFKB1 | |
| SCHEMBL7151133 | 0.73 | GNAI3 (0.38) | GAALIPEL3MBTL1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552264-A1 | N-(2-ALKYL-3-MERCAPTOGLUTARYL)-AMINO-DIAZA CYCLOALKANONE DERIVATIVES AND THEIR USE AS COLLAGENASE INHIBITORS | BEECHAM GROUP plc (GB) | 1993-07-28 | — | — | EP | disclosed |
| WO-1992006966-A1 | N-(2-ALKYL-3-MERCAPTOGLUTARYL)-AMINO-DIAZA CYCLOALKANONE DERIVATIVES AND THEIR USE AS COLLAGENASE INHIBITORS | BEECHAM GROUP PLC (GB) | 1992-04-30 | — | — | WO | disclosed |