Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL704133 | 0.84 | L3MBTL1 (0.53) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL1301049 | 0.82 | L3MBTL1 (0.70) | L3MBTL1RAB9ASMN1; SMN2TSHRMAPK1 | |
| SCHEMBL7996145 | 0.80 | L3MBTL1 (0.61) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL7411441 | 0.79 | L3MBTL1 (0.71) | L3MBTL1RAB9ASMN1; SMN2TSHRMAPK1 | |
| SCHEMBL7999728 | 0.76 | PLA2G2A (0.42) | FBP1SMN1; SMN2TSHRLMNAALDH1A1 | |
| SCHEMBL2055354 | 0.75 | L3MBTL1 (0.59) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL7604286 | 0.74 | L3MBTL1 (0.62) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL23667729 | 0.73 | L3MBTL1 (0.53) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL7427014 | 0.73 | L3MBTL1 (0.45) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL7996346 | 0.73 | L3MBTL1 (0.45) | L3MBTL1MPORAB9ASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492384-B1 | Imidazo (4,5-C) pyridine-4-one derivatives with factor XA inhibiting effect | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |
| EP-1157010-A1 | PYRAZOLE-3-ON-DERIVATIVE AS FACTOR XA INHIBITORS | MERCK PATENT GmbH (DE) | 2001-11-28 | — | — | EP | disclosed |
| EP-1117664-A1 | IMIDAZO[4,5-C-]-PYRIDINE-4-ONE DERIVATIVES WITH FACTOR XA INHIBITING EFFECT | MERCK PATENT GmbH (DE) | 2001-07-25 | — | — | EP | disclosed |
| WO-2001051484-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2001-07-19 | — | — | WO | disclosed |
| EP-1107954-A1 | 2-OXO-$i(2H)-QUINOLINE DERIVATIVES | MERCK PATENT GmbH (DE) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000051989-A1 | PYRAZOLE-3-ON-DERIVATIVE AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2000-09-08 | — | — | WO | disclosed |
| WO-2000020416-A1 | IMIDAZO[4,5-C-]-PYRIDINE-4-ONE DERIVATIVES WITH FACTOR XA INHIBITING EFFECT | MERCK PATENT GMBH (DE) | 2000-04-13 | — | — | WO | disclosed |
| WO-2000012479-A1 | 2-OXO-2H-QUINOLINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-03-09 | — | — | WO | disclosed |