Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL704133 | 0.84 | L3MBTL1 (0.53) | L3MBTL1MAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL1890535 | 0.79 | GPR55 (0.38) | MAPTSMN1; SMN2ALDH1A1LMNAGPR55 | |
| SCHEMBL7097837 | 0.78 | L3MBTL1 (0.46) | L3MBTL1MAPTHSD17B10NPSR1KDM4E | |
| SCHEMBL7996346 | 0.76 | L3MBTL1 (0.45) | L3MBTL1MAPTHSD17B10NPSR1KDM4E | |
| SCHEMBL5316479 | 0.75 | NPC1 (0.54) | L3MBTL1MAPTHSD17B10NPSR1KDM4E | |
| SCHEMBL10892045 | 0.75 | ALDH1A1 (0.57) | HSD17B10GAAALDH1A1HPGDLMNA | |
| SCHEMBL7366377 | 0.73 | L3MBTL1 (0.53) | L3MBTL1HSD17B10KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL31069896 | 0.73 | TRPA1 (0.35) | ALDH1A1GPR55TSHR | |
| SCHEMBL31069897 | 0.73 | TRPA1 (0.35) | ALDH1A1GPR55TSHR | |
| SCHEMBL1301049 | 0.73 | L3MBTL1 (0.70) | L3MBTL1MAPTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107954-A1 | 2-OXO-$i(2H)-QUINOLINE DERIVATIVES | MERCK PATENT GmbH (DE) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012479-A1 | 2-OXO-2H-QUINOLINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-03-09 | — | — | WO | disclosed |