Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 4/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367718 | 0.86 | KDM2B (0.52) | KDM2BLTA4HEPHX2HTTL3MBTL1 | |
| SCHEMBL7337102 | 0.80 | YAP1 (0.47) | KDM2BLTA4HEPHX2L3MBTL1KDM4E | |
| SCHEMBL7337109 | 0.79 | YAP1 (0.49) | KDM2BLTA4HEPHX2KDM4ERAB9A | |
| SCHEMBL7367889 | 0.76 | HTT (0.57) | LTA4HHTTL3MBTL1KDM4ENPC1 | |
| SCHEMBL7369353 | 0.75 | RAB9A (0.56) | LTA4HEPHX2HTTL3MBTL1KDM4E | |
| SCHEMBL7366593 | 0.74 | UTS2R (0.46) | KDM2B | |
| SCHEMBL8177808 | 0.73 | KDM2B (0.62) | KDM2BLTA4HEPHX2HTTL3MBTL1 | |
| SCHEMBL7366749 | 0.73 | LTA4H (0.52) | LTA4HEPHX2HTTL3MBTL1KDM4E | |
| SCHEMBL7375300 | 0.72 | NPC1 (0.52) | LTA4HNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7342585 | 0.71 | YAP1 (0.47) | LTA4HEPHX2L3MBTL1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998054123-A1 | SUBSTITUTED PEPTIDYLAMINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1998-12-03 | — | — | WO | disclosed |