Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 6/20 | 0.48 |
| ▸ | MMP13 | P45452 | 6/20 | 0.48 |
| ▸ | MMP1 | P03956 | 5/20 | 0.48 |
| ▸ | MMP3 | P08254 | 2/20 | 0.47 |
| ▸ | MMP10 | P09238 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6933911 | 0.87 | MMP13 (0.55) | MMP9MMP13MMP1APPCYP3A4 | |
| SCHEMBL6566720 | 0.86 | MMP3 (0.56) | MMP9MMP13MMP1MMP3MMP10 | |
| SCHEMBL7364431 | 0.84 | ADAM17 (0.59) | MMP9MMP13MMP1ADAM17 | |
| Hydrochloric Acid SCHEMBL6265694 | 0.84 | ADAM17 (0.58) | MMP9MMP13MMP1CYP3A4CYP2D6 | |
| SCHEMBL6565388 | 0.78 | MMP9 (0.73) | MMP9MMP13MMP1APPCYP3A4 | |
| SCHEMBL6567101 | 0.78 | MMP9 (0.67) | MMP9MMP13MMP1MMP3MMP10 | |
| SCHEMBL6566829 | 0.76 | MMP9 (0.68) | MMP9MMP13MMP1MMP3APP | |
| SCHEMBL6565593 | 0.75 | MMP9 (0.69) | MMP9MMP13MMP1APPCYP3A4 | |
| SCHEMBL6566808 | 0.74 | CYP3A4 (0.80) | MMP9MMP13MMP1CYP3A4CYP2D6 | |
| SCHEMBL6567079 | 0.74 | MMP9 (0.71) | MMP9MMP13MMP1MMP3APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252143-A1 | METHOD FOR PREPARING ALPHA-SULFONYL HYDROXAMIC ACID DERIVATIVES | American Cyanamid Company (US) | 2002-10-30 | — | — | EP | disclosed |
| US-20020099035-A1 | Method for preparing alpha-sulfonyl hydroxamic acid derivatives | WYETH HOLDINGS CORPORATION | 2002-07-25 | — | — | US | disclosed |
| WO-2001055112-A1 | METHOD FOR PREPARING ALPHA-SULFONYL HYDROXAMIC ACID DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 2001-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099035-A1 | Method for preparing alpha-sulfonyl hydroxamic acid derivatives | MMP25, ADAMTS5, MMP9 | MMP9 3/4885MMP13 22/4885MMP1 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.