Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KLK1 | P06870 | 2/20 | 0.32 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367484 | 0.95 | AGTR1 (0.35) | AGTR1MEN1KMT2AKDR | |
| SCHEMBL7371013 | 0.84 | AGTR1 (0.32) | AGTR1MEN1KMT2AKDRF2 | |
| Trifluoroacetic Acid SCHEMBL7372144 | 0.82 | CA1 (0.36) | KLK1KLK5F2 | |
| Trifluoroacetic Acid SCHEMBL7444932 | 0.78 | F2 (0.41) | F2 | |
| Hydrochloric Acid SCHEMBL7447049 | 0.77 | CA1 (0.39) | F2 | |
| Trifluoroacetic Acid SCHEMBL7368775 | 0.77 | ITGB3 (0.44) | — | |
| Trifluoroacetic Acid SCHEMBL7450905 | 0.76 | CA2 (0.44) | — | |
| Trifluoroacetic Acid SCHEMBL7369183 | 0.76 | PLAU (0.43) | KMT2AF2 | |
| Trifluoroacetic Acid SCHEMBL7377943 | 0.75 | TMPRSS15 (0.44) | — | |
| Trifluoroacetic Acid SCHEMBL6434344 | 0.75 | KLK1 (0.38) | AGTR1MEN1KMT2AKLK1KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242120-A2 | COMBINATIONS OF GROWTH FACTORS AND I:UPA OR I:MMP FOR THE TREATMENT OF DAMAGED TISSUE | Pfizer Limited (GB) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001049309-A2 | COMBINATIONS OF GROWTH FACTORS AND I: UPA OR I: MMP FOR THE TREATMENT OF DAMAGED TISSUE | PFIZER LIMITED (GB) | 2001-07-12 | — | — | WO | disclosed |
| EP-1077945-A1 | ISOQUINOLINES AS UROKINASE INHIBITORS | PFIZER INC. (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-2000005214-A2 | ISOQUINOLINES AS UROKINASE INHIBITORS | PFIZER INC. (US) | 2000-02-03 | — | — | WO | disclosed |