Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 12/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7375959 | 0.84 | F2 (0.37) | F2F10PLAUGPBAR1 | |
| Trifluoroacetic Acid SCHEMBL6433676 | 0.81 | PLAU (0.48) | PLAU | |
| Trifluoroacetic Acid SCHEMBL7372144 | 0.80 | CA1 (0.36) | F2 | |
| Trifluoroacetic Acid SCHEMBL7368253 | 0.78 | AGTR1 (0.32) | F2 | |
| Trifluoroacetic Acid SCHEMBL7368775 | 0.78 | ITGB3 (0.44) | — | |
| Trifluoroacetic Acid SCHEMBL7450905 | 0.77 | CA2 (0.44) | — | |
| Trifluoroacetic Acid SCHEMBL7377943 | 0.76 | TMPRSS15 (0.44) | PRSS1 | |
| Trifluoroacetic Acid SCHEMBL6433378 | 0.76 | F2 (0.33) | F2PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL6435141 | 0.76 | PLAU (0.49) | PLAU | |
| Trifluoroacetic Acid SCHEMBL6432736 | 0.76 | PLAU (0.46) | PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242120-A2 | COMBINATIONS OF GROWTH FACTORS AND I:UPA OR I:MMP FOR THE TREATMENT OF DAMAGED TISSUE | Pfizer Limited (GB) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001049309-A2 | COMBINATIONS OF GROWTH FACTORS AND I: UPA OR I: MMP FOR THE TREATMENT OF DAMAGED TISSUE | PFIZER LIMITED (GB) | 2001-07-12 | — | — | WO | disclosed |