Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | HCK | P08631 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360998 | 0.91 | HPGD (0.52) | KAT2BHPGDMAPTL3MBTL1POLB | |
| SCHEMBL7362432 | 0.89 | MKNK1 (0.44) | KAT2BHPGDMAPTL3MBTL1POLB | |
| SCHEMBL7363887 | 0.87 | KAT2B (0.52) | KAT2BHPGDMAPTL3MBTL1POLB | |
| SCHEMBL7366633 | 0.87 | NCOA1 (0.46) | KAT2BHPGDMAPTL3MBTL1POLB | |
| SCHEMBL7370561 | 0.85 | L3MBTL1 (0.47) | KAT2BMAPTL3MBTL1POLBADORA1 | |
| SCHEMBL7369331 | 0.82 | SRC (0.46) | KAT2BHPGDMAPTL3MBTL1ADORA1 | |
| SCHEMBL7365898 | 0.81 | PDE4B (0.49) | KAT2BHPGDMAPTADORA1RORC | |
| SCHEMBL7370202 | 0.80 | MKNK1 (0.44) | KAT2BHPGDMAPTL3MBTL1POLB | |
| SCHEMBL7367332 | 0.80 | HTT (0.53) | KAT2BHPGDL3MBTL1KMT2ARORC | |
| SCHEMBL7369488 | 0.79 | HPGD (0.50) | KAT2BHPGDMAPTPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612321-A1 | PYRIDO PYRIDAZINONE AND PYRIDAZINTHIONE COMPOUNDS WITH PDE IV INHIBITING ACTIVITY | SYNTEX (U.S.A.) INC. (US) | 1994-08-31 | — | — | EP | disclosed |
| WO-1993007146-A1 | BENZO AND PYRIDO PYRIDAZINONE AND PYRIDAZINTHIONE COMPOUNDS WITH PDE IV INHIBITING ACTIVITY | SYNTEX (U.S.A.) INC. (US) | 1993-04-15 | — | — | WO | disclosed |