Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.44 |
| ▸ | LAP3 | P28838 | 3/20 | 0.43 |
| ▸ | ANPEP | P15144 | 2/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ECE1 | P42892 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363022 | 0.79 | CTRB1 (0.52) | MEN1CYP1A2KMT2APIN1ACE2 | |
| SCHEMBL7370001 | 0.79 | NPC1 (0.51) | MEN1CYP1A2KMT2AANPEPMME | |
| SCHEMBL7369997 | 0.79 | NPC1 (0.51) | MEN1CYP1A2KMT2AANPEPMME | |
| SCHEMBL7359942 | 0.77 | CTRB1 (0.50) | MEN1CYP1A2KMT2APIN1CTRB1 | |
| SCHEMBL7365324 | 0.75 | MME (0.66) | MEN1CYP1A2KMT2APIN1CTRB1 | |
| SCHEMBL7367162 | 0.75 | NAALAD2 (0.58) | MEN1KMT2AMME | |
| SCHEMBL7367157 | 0.75 | NAALAD2 (0.58) | MEN1KMT2AMME | |
| SCHEMBL7363566 | 0.73 | PIN1 (0.59) | MEN1CYP1A2KMT2APIN1CTRB1 | |
| SCHEMBL7370588 | 0.73 | MME (0.59) | MME | |
| SCHEMBL7443024 | 0.73 | PIN1 (0.49) | MEN1CYP1A2KMT2APIN1CTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117429-B1 | PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES | SCHERING CORPORATION (US) | 1987-09-02 | — | — | EP | claimed |
| EP-0117429-A1 | Phosphorous containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1984-09-05 | — | — | EP | claimed |
| EP-0117429-B1 | PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES | SCHERING CORPORATION (US) | 1987-09-02 | — | — | EP | disclosed |
| EP-0117429-A1 | Phosphorous containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1984-09-05 | — | — | EP | disclosed |