Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 4/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3244408 | 0.77 | NPSR1 (0.43) | SMN1; SMN2NPSR1LMNAMAPTXBP1 | |
| SCHEMBL2037726 | 0.76 | PTGS2 (0.46) | SMN1; SMN2LMNAMAPTCES2CES1 | |
| SCHEMBL8017607 | 0.74 | CES2 (0.44) | SMN1; SMN2NPSR1LMNAMAPTXBP1 | |
| SCHEMBL7369308 | 0.74 | LMNA (0.43) | SMN1; SMN2NPSR1LMNAMAPTXBP1 | |
| SCHEMBL5366753 | 0.74 | ALDH1A1 (0.43) | SMN1; SMN2NPSR1LMNAMAPTXBP1 | |
| SCHEMBL15956056 | 0.72 | TSHR (0.52) | SMN1; SMN2NPSR1LMNAMAPTXBP1 | |
| SCHEMBL28685314 | 0.72 | PKM (0.52) | SMN1; SMN2NPSR1LMNAMAPTXBP1 | |
| SCHEMBL10492355 | 0.72 | SMN1; SMN2 (0.40) | SMN1; SMN2NPSR1LMNAMAPTXBP1 | |
| SCHEMBL20953736 | 0.72 | TSHR (0.41) | SMN1; SMN2NPSR1LMNAMAPTXBP1 | |
| SCHEMBL5664608 | 0.72 | ALDH1A1 (0.46) | SMN1; SMN2NPSR1LMNAMAPTXBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722436-A4 | MERCAPTOSULFIDE METALLOPROTEINASE INHIBITORS | UNIV FLORIDA STATE (US) | 1996-11-20 | — | — | EP | disclosed |
| EP-0722436-A1 | MERCAPTOSULFIDE METALLOPROTEINASE INHIBITORS | FLORIDA STATE UNIVERSITY (US) | 1996-07-24 | — | — | EP | disclosed |
| WO-1995009833-A1 | MERCAPTOSULFIDE METALLOPROTEINASE INHIBITORS | FLORIDA STATE UNIVERSITY (US) | 1995-04-13 | — | — | WO | disclosed |