Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 3/20 | 0.47 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370252 | 0.84 | ALDH1A1 (0.53) | NPY5RLMNAALDH1A1HPGDHSD17B10 | |
| SCHEMBL7372716 | 0.83 | ALDH1A1 (0.43) | LMNAALDH1A1HPGDHSD17B10HPSE | |
| SCHEMBL7368078 | 0.81 | NPY5R (0.53) | NPY5RFOXO1MKNK1MKNK2SMPD3 | |
| SCHEMBL7372225 | 0.78 | NPY5R (0.62) | NPY5RMKNK1MKNK2SMPD3 | |
| SCHEMBL7370057 | 0.78 | LMNA (0.43) | LMNAMKNK1MKNK2PDE10AMAPK1 | |
| SCHEMBL7369602 | 0.76 | NPY5R (0.56) | NPY5RMKNK1MKNK2SMPD3PDE10A | |
| SCHEMBL7365692 | 0.75 | NPY5R (0.57) | NPY5RALDH1A1HPGDHSD17B10SMPD3 | |
| SCHEMBL7370913 | 0.75 | NPY5R (0.57) | NPY5RALDH1A1HPGDHSD17B10SMPD3 | |
| SCHEMBL7371445 | 0.74 | NPY5R (0.67) | NPY5RALDH1A1SMPD3 | |
| SCHEMBL7369412 | 0.74 | PDGFRB (0.41) | NPY5RLMNAHPSEMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | claimed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | claimed |
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |