Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.52 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.52 |
| ▸ | FEN1 | P39748 | 1/20 | 0.52 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.51 |
| ▸ | DHODH | Q02127 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | STAT1 | P42224 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29093221 | 0.86 | PIN1 (0.69) | PIN1CYP1A2MAPK1CASP1CYP2C19 | |
| SCHEMBL7977705 | 0.85 | DHODH (0.54) | PIN1NPY5RDHODHKDM4ELDHA | |
| SCHEMBL7992089 | 0.85 | MAPK14 (0.62) | PIN1CYP1A2MAPK1CASP1CYP2C19 | |
| SCHEMBL7989683 | 0.82 | ALDH1A1 (0.48) | PIN1CYP1A2MAPK1CASP1CYP2C19 | |
| SCHEMBL7988268 | 0.82 | PIN1 (0.52) | PIN1CYP1A2MAPK1CASP1CYP2C19 | |
| SCHEMBL21652629 | 0.81 | PIN1 (0.71) | PIN1CYP1A2MAPK1CASP1CYP2C19 | |
| SCHEMBL10649656 | 0.79 | PIN1 (0.72) | PIN1CYP1A2MAPK1CASP1CYP2C19 | |
| SCHEMBL7978027 | 0.78 | KDM4E (0.67) | PIN1CYP1A2MAPK1CASP1CYP2C19 | |
| SCHEMBL7372293 | 0.77 | MKNK1 (0.58) | CYP1A2CYP2C19NPY5RDHODHKDM4E | |
| Hydrochloric Acid SCHEMBL7978210 | 0.77 | RAB9A (0.53) | CYP1A2MAPK1KDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |