Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.68 |
| ▸ | MEN1 | O00255 | 6/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | ACLY | P53396 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | CRHBP | P24387 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370095 | 0.88 | TSHR (0.77) | KMT2AMEN1GAATSHRKDM4E | |
| SCHEMBL13011714 | 0.86 | KMT2A (0.74) | KMT2AMEN1GAATSHRKDM4E | |
| SCHEMBL3283149 | 0.85 | KMT2A (0.69) | KMT2AMEN1GAATSHRKDM4E | |
| SCHEMBL7457320 | 0.85 | CASP3 (0.64) | KMT2AMEN1GAATSHRKDM4E | |
| SCHEMBL23200347 | 0.83 | KEAP1 (0.65) | KMT2AMEN1GAATSHRKDM4E | |
| SCHEMBL14659917 | 0.81 | KMT2A (0.52) | KMT2AMEN1GAATSHRKDM4E | |
| SCHEMBL1981780 | 0.80 | METAP2 (0.68) | KMT2AMEN1GAATSHRKDM4E | |
| SCHEMBL7569668 | 0.80 | KMT2A (0.76) | KMT2AMEN1GAATSHRKDM4E | |
| SCHEMBL5467189 | 0.79 | DDX3X (0.66) | KMT2AMEN1GAAKDM4ELMNA | |
| SCHEMBL9997041 | 0.79 | AKR1C3 (0.59) | KMT2AMEN1GAATSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001074786-A1 | HETEROBIARYLSULPHONAMIDES AND THEIR USE AS PDE 7 INHIBITORS | DARWIN DISCOVERY LIMITED (GB) | 2001-10-11 | — | — | WO | disclosed |