Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.32 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.31 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.31 |
| ▸ | F7 | P08709 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
| ▸ | F9 | P00740 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7372930 | 0.88 | BCAT2 (0.34) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 | |
| SCHEMBL7376531 | 0.86 | BCAT2 (0.33) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 | |
| SCHEMBL7368634 | 0.86 | EPHX1 (0.36) | PKMBCAT2MTNR1AMTNR1BSLC1A2 | |
| SCHEMBL7375836 | 0.84 | GPR88 (0.33) | SMN1; SMN2BCAT2SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL7372945 | 0.83 | POLB (0.33) | BCAT2SLC1A2SLC1A1F7 | |
| SCHEMBL7373098 | 0.79 | SMN1; SMN2 (0.33) | SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL9128947 | 0.72 | NPY4R (0.44) | — | |
| SCHEMBL8169663 | 0.71 | LMNA (0.37) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 | |
| Hydrochloric Acid SCHEMBL6947022 | 0.69 | GABBR2 (0.56) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 | |
| SCHEMBL7423519 | 0.68 | GABBR2 (0.49) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749316-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 1999-04-21 | — | — | EP | disclosed |
| EP-0749316-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1996-12-27 | — | — | EP | disclosed |
| WO-1995023608-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1995-09-08 | — | — | WO | disclosed |