Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.36 |
| ▸ | NAAA | Q02083 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557692 | 0.79 | C3AR1 (0.36) | HDAC1HDAC7NAAAITGB3ITGA2B | |
| SCHEMBL8560464 | 0.77 | C3AR1 (0.39) | ALDH1A1CYP1A2CYP2D6PKMSMN1; SMN2 | |
| SCHEMBL9128947 | 0.75 | NPY4R (0.44) | C3AR1 | |
| SCHEMBL8174677 | 0.74 | TPSAB1 (0.39) | CYP1A2CYP2D6PKMSMN1; SMN2NPSR1 | |
| SCHEMBL11211550 | 0.72 | ALDH1A1 (0.40) | LMNAALDH1A1CYP1A2CYP2D6PKM | |
| SCHEMBL9213580 | 0.72 | CYP2D6 (0.42) | LMNAALDH1A1CYP1A2CYP2D6PKM | |
| SCHEMBL11095898 | 0.71 | CNR2 (0.44) | HDAC6HDAC8ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL7373889 | 0.71 | SMN1; SMN2 (0.38) | ALDH1A1CYP1A2CYP2D6PKMSMN1; SMN2 | |
| SCHEMBL7368634 | 0.68 | EPHX1 (0.36) | PKMBCAT2 | |
| SCHEMBL8619040 | 0.68 | ITGB3 (0.52) | LMNAHDAC6HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114328-A | ANTICOAGULANTS; BLOOD DISORDERS | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-09-05 | — | — | US | disclosed |
| US-5849736-A | Isoxazoline and isoxazole fibrinogen receptor antagonists | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-12-15 | — | — | US | disclosed |