Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.56 |
| ▸ | CA9 | Q16790 | 5/20 | 0.56 |
| ▸ | TNF | P01375 | 1/20 | 0.56 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.56 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.56 |
| ▸ | TERT | O14746 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | SHBG | P04278 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8515595 | 0.86 | TERT (0.72) | CA12CA9TERTPOLBMAPT | |
| SCHEMBL15477703 | 0.75 | ATP1A1 (0.64) | CA12CA9TNFNOD2NOD1 | |
| SCHEMBL8877681 | 0.72 | ALDH1A1 (0.56) | POLBMAPTPKMKDM4EGAA | |
| SCHEMBL18073978 | 0.72 | ESR2 (0.63) | CA12CA9TNFNOD2NOD1 | |
| SCHEMBL28192062 | 0.72 | ESR2 (0.58) | CA12CA9TNFNOD2NOD1 | |
| SCHEMBL8513483 | 0.72 | TERT (0.68) | TERTPOLBMAPTPKMKDM4E | |
| SCHEMBL5569925 | 0.72 | ABCG2 (0.68) | CA12CA9TERTPOLBMAPT | |
| SCHEMBL31438664 | 0.72 | ABCG2 (0.68) | CA12CA9TERTPOLBMAPT | |
| SCHEMBL9835933 | 0.72 | PTGS2 (0.71) | ESR2MAPTKDM4ESMN1; SMN2LMNA | |
| SCHEMBL4300469 | 0.71 | ALOX15 (0.74) | CA12CA9TNFNOD2NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115718-A1 | HYDROXYFLAVONE DERIVATIVES AS TAU PROTEIN KINASE 1 INHIBITORS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000017184-A1 | HYDROXYFLAVONE DERIVATIVES AS TAU PROTEIN KINASE 1 INHIBITORS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-03-30 | — | — | WO | disclosed |