Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8432465 | 0.86 | KEAP1 (0.50) | ALDH1A1LMNAKEAP1MAPTHPGD | |
| SCHEMBL7281766 | 0.83 | NPC1 (0.56) | ALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL4243105 | 0.82 | ALDH1A1 (0.57) | ALDH1A1LMNATSHRHPGDTDP1 | |
| SCHEMBL7380269 | 0.81 | ALDH1A1 (0.64) | ALDH1A1LMNAHPGDADRB2HTT | |
| SCHEMBL6844310 | 0.80 | KEAP1 (0.53) | ALDH1A1LMNAKEAP1TSHRMAPT | |
| SCHEMBL27552 | 0.79 | ALDH1A1 (0.76) | ALDH1A1LMNATSHRMAPTTDP1 | |
| SCHEMBL27564119 | 0.78 | ALDH1A1 (0.59) | ALDH1A1LMNAMAPTHPGDL3MBTL1 | |
| SCHEMBL9844983 | 0.78 | ALDH1A1 (0.53) | ALDH1A1LMNATSHRMAPTL3MBTL1 | |
| SCHEMBL10438855 | 0.78 | CYP4F2 (0.58) | ALDH1A1LMNATSHRMAPTHPGD | |
| SCHEMBL25412081 | 0.77 | KDM4E (0.42) | ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002051810-A2 | INTEGRIN RECEPTOR LIGANDS | ABBOTT GMBH & CO. KG (DE) | 2002-07-04 | — | — | WO | disclosed |