Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.64 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | F2R | P25116 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4243105 | 0.83 | ALDH1A1 (0.57) | ALDH1A1LMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL5595491 | 0.81 | ALDH1A1 (0.71) | ALDH1A1ADRB2BCAT2CYP3A4CYP2C19 | |
| SCHEMBL7375283 | 0.81 | ALDH1A1 (0.49) | ALDH1A1ADRB2LMNAHPGDHTT | |
| SCHEMBL1072315 | 0.80 | ALDH1A1 (0.73) | ALDH1A1ADRB2BCAT2CYP3A4CYP2C19 | |
| SCHEMBL27552 | 0.80 | ALDH1A1 (0.76) | ALDH1A1LMNAKDM4EPOLBHTT | |
| SCHEMBL19259498 | 0.79 | BCAT2 (0.72) | ALDH1A1ADRB2BCAT2CYP3A4CYP2C19 | |
| SCHEMBL7281766 | 0.79 | NPC1 (0.56) | ALDH1A1SMN1; SMN2NPC1HPGDRAB9A | |
| SCHEMBL6271944 | 0.79 | ALDH1A1 (0.68) | ALDH1A1ADRB2BCAT2CYP3A4CYP2C19 | |
| SCHEMBL9844983 | 0.79 | ALDH1A1 (0.53) | ALDH1A1CYP3A4CYP2C19CYP1A2LMNA | |
| SCHEMBL10438855 | 0.79 | CYP4F2 (0.58) | ALDH1A1LMNAKDM4ESMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002051810-A2 | INTEGRIN RECEPTOR LIGANDS | ABBOTT GMBH & CO. KG (DE) | 2002-07-04 | — | — | WO | disclosed |