Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 3/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FPR1 | P21462 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12825712 | 0.77 | STING1 (0.45) | KDM4EMEN1ALDH1A1CYP3A4HPGD | |
| SCHEMBL4035629 | 0.74 | ALOX5 (0.48) | KDM4EELANEABCG2ABCB1ALOX15 | |
| SCHEMBL7375725 | 0.73 | CDK1 (0.44) | KDM4EMEN1ALDH1A1CYP3A4HPGD | |
| SCHEMBL13181024 | 0.73 | ALDH1A1 (0.47) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL8811366 | 0.70 | KDM4E (0.58) | KDM4EMEN1ALDH1A1CYP3A4HPGD | |
| SCHEMBL13648770 | 0.68 | BID (0.43) | ELANEABCB1CTSGALOX5PTGS2 | |
| SCHEMBL7378571 | 0.68 | ALDH1A1 (0.73) | KDM4EMEN1ALDH1A1CYP3A4HPGD | |
| SCHEMBL10966060 | 0.68 | GLA (0.45) | KDM4EHPGDABCG2 | |
| SCHEMBL12825530 | 0.68 | STING1 (0.42) | KDM4EMEN1ALDH1A1CYP3A4KMT2A | |
| SCHEMBL7378573 | 0.68 | ABCG2 (0.62) | KDM4EMEN1ALDH1A1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115718-A1 | HYDROXYFLAVONE DERIVATIVES AS TAU PROTEIN KINASE 1 INHIBITORS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000017184-A1 | HYDROXYFLAVONE DERIVATIVES AS TAU PROTEIN KINASE 1 INHIBITORS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-03-30 | — | — | WO | disclosed |