Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 10/20 | 0.44 |
| ▸ | CTSS | P25774 | 3/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 2/20 | 0.43 |
| ▸ | MMP12 | P39900 | 2/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.42 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.41 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7160684 | 0.94 | CA5A (0.51) | CA5ACA1CTSKCTSSCTSL | |
| SCHEMBL5934952 | 0.94 | CA5A (0.51) | CA5ACA1CTSKCTSSCTSL | |
| SCHEMBL7376478 | 0.83 | PSMB1 (0.47) | CA5ACA1CTSKCTSSCTSL | |
| SCHEMBL8042541 | 0.83 | CASP1 (0.49) | CA5ACA1CTSKCTSSCTSL | |
| SCHEMBL5934907 | 0.83 | CA5A (0.52) | CA5ACA1CTSKCTSSCTSL | |
| SCHEMBL7160690 | 0.81 | MMP12 (0.49) | CA5ACA1CTSKCTSSCTSL | |
| SCHEMBL5934954 | 0.80 | MMP12 (0.49) | CA5ACA1CTSKCTSSCTSL | |
| SCHEMBL7966128 | 0.78 | CTSK (0.52) | CA5ACA1CTSKCTSSCTSL | |
| SCHEMBL5934909 | 0.76 | CASP1 (0.49) | CA5ACA1CTSKCTSSCTSL | |
| SCHEMBL7163257 | 0.73 | CTSK (0.46) | CA5ACA1CTSKCTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934291-A4 | — | SMITHKLINE BEECHAM CORP (US) | 1999-08-11 | — | — | EP | disclosed |
| EP-0934291-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1997016433-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-09 | — | — | WO | disclosed |