Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | CTSK | P43235 | 8/20 | 0.48 |
| ▸ | CTSB | P07858 | 6/20 | 0.48 |
| ▸ | CTSS | P25774 | 4/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 8/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5934907 | 0.89 | CA5A (0.52) | CASP1CTSKCTSBCTSSCA5A | |
| SCHEMBL5934952 | 0.88 | CA5A (0.51) | CTSKCTSBCTSSCA5ACAPN1 | |
| SCHEMBL5934909 | 0.88 | CASP1 (0.49) | CASP1CTSKCTSBCTSSCA5A | |
| SCHEMBL7163257 | 0.84 | CTSK (0.46) | CASP1CTSKCTSBCTSSCA5A | |
| SCHEMBL7378360 | 0.83 | CA5A (0.46) | CTSKCTSBCTSSCA5ACAPN1 | |
| SCHEMBL6685713 | 0.82 | MMP12 (0.43) | CASP1CTSKCTSBCTSSCA5A | |
| SCHEMBL7160684 | 0.81 | CA5A (0.51) | CTSKCTSBCTSSCA5ACAPN1 | |
| SCHEMBL5934954 | 0.81 | MMP12 (0.49) | CASP1CTSKCTSBCTSSCA5A | |
| SCHEMBL7160690 | 0.80 | MMP12 (0.49) | CTSKCTSBCTSSCA5ACA1 | |
| SCHEMBL6683187 | 0.79 | MMP12 (0.40) | CASP1CTSKCTSBCTSSCA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057362-A | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2000-05-02 | — | — | US | disclosed |