Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7386171 | 1.00 | AGTR2 (0.44) | AGTR2RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5314984 | 0.81 | FFAR1 (0.52) | RAB9ANPC1SMN1; SMN2ALDH1A1FFAR1 | |
| SCHEMBL16468044 | 0.78 | ALDH1A1 (0.41) | RAB9ASMN1; SMN2ALDH1A1KMT2ACRBN | |
| SCHEMBL15477388 | 0.77 | SMN1; SMN2 (0.48) | AGTR2RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL18862951 | 0.75 | HSD11B1 (0.48) | — | |
| SCHEMBL18862950 | 0.75 | HSD11B1 (0.48) | — | |
| SCHEMBL6966938 | 0.73 | ITGB1 (0.42) | AGTR2RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5180568 | 0.72 | KDM1A (0.48) | RAB9ANPC1ALDH1A1HPGDKMT2A | |
| SCHEMBL26927141 | 0.72 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL4158989 | 0.71 | ABHD6 (0.47) | RAB9ANPC1ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023265-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF HCMV INFECTIONS | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999018073-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF HCMV INFECTIONS | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 1999-04-15 | — | — | WO | disclosed |